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Detroit Lions vs Buffalo Bills

Highmark Stadium

Team Season Average

Season averages are not available for this game yet.

Odds

SportsbookSpread (BUF)TotalDET MLBUF ML
DDraftKings-19.557.5+1240-2300
FFanDuel-18.557.5+1100-4000
BBetMGM-18.557.5+1100-2500
CCaesars-18.558.5+900-2500
BBetOnline-5.554.5+212-257
BBetRivers-1857.5+1200-5000
BBetus-5.554.5+210-250
BBovada-19.558+750-1600
FFanatics-18.557.5+1000-2200
LLowVig-5.554.5+212-257

Detroit Lions vs Buffalo Bills: Final Score & Recap

The Buffalo Bills beat the Detroit Lions 41-31 in this NFL game at Highmark Stadium on Thursday, September 17, 2026. The line score, team and player box scores, and scoring summary are in the Game Stats tab.

Team pages: Detroit Lions · Buffalo Bills

Detroit Lions vs Buffalo Bills Odds

DraftKings lists the Buffalo Bills at BUF -19.5 on the spread, with the total set at 57.5. Moneylines are Detroit Lions +1240 and Buffalo Bills -2300. Those are the closing numbers; the odds table above compares every book we track.

See the full NFL odds board and the NFL schedule. Looking for a side rather than a line? See today's NFL picks. For the model's reasoning, read our AI NFL predictions.

Detroit Lions vs Buffalo Bills — Common Questions

Who won Detroit Lions vs Buffalo Bills?+

The Buffalo Bills beat the Detroit Lions 41-31 on Sep 17, 2026 at Highmark Stadium. The full box score and line score are on this page.

What are the odds for Detroit Lions vs Buffalo Bills?+

DraftKings lists the Buffalo Bills at BUF -19.5 on the spread, with the total set at 57.5. Moneylines are Detroit Lions +1240 and Buffalo Bills -2300. Those are the closing numbers; the odds table above compares every book we track.

Where was Detroit Lions vs Buffalo Bills played?+

The game was at Highmark Stadium.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.

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