Player prop lines have not been posted for this matchup yet.
New England Patriots vs Buffalo Bills: Matchup Preview
The New England Patriots (1-2) visit the Buffalo Bills (3-0) in this NFL game, which kicks off on Sunday, October 4, 2026 at 1:00 PM ET at Highmark Stadium. The New England Patriots come in with 7 days of rest; the Buffalo Bills have 7 days of rest.
DraftKings lists the Buffalo Bills at BUF -7 on the spread, with the total set at 49.5. Moneylines are New England Patriots +245 and Buffalo Bills -305. Lines move up to game time; the odds table above compares every book we track so you can shop the number.
New England Patriots vs Buffalo Bills — Common Questions
When do the New England Patriots play the Buffalo Bills?+
New England Patriots at Buffalo Bills kicks off on Sunday, October 4, 2026 at 1:00 PM ET at Highmark Stadium. Times are shown in Eastern Time.
What are the odds for New England Patriots vs Buffalo Bills?+
DraftKings lists the Buffalo Bills at BUF -7 on the spread, with the total set at 49.5. Moneylines are New England Patriots +245 and Buffalo Bills -305. Lines move up to game time; the odds table above compares every book we track so you can shop the number.
Where is New England Patriots vs Buffalo Bills being played?+
The game is at Highmark Stadium.
Where can I follow the New England Patriots vs Buffalo Bills live score?+
This page carries the live score, the period-by-period line score, and the box score while the game is on, then the final result and full stats once it ends.
Is Stat Sniper a sportsbook?+
No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.
Stat Sniper is an analysis tool, not a sportsbook. Chad's picks are projections and can be wrong. Odds change; check your sportsbook before betting. You must be 21+ (18+ in some states) and located where sports betting is legal. Gambling problem? Call 1-800-GAMBLER.
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