Pittsburgh Pirates vs St. Louis Cardinals AI Sports Picks & Predictions

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MLB

Pittsburgh PiratesPIT

6–2

Final

St. Louis CardinalsSTL

Busch Stadium

Team Season Averages

Pittsburgh PiratesLeads 13 of 17

St. Louis CardinalsLeads 4 of 17

Batting

4.94Runs per game4.52
0.252Batting average0.240
0.335On-base percentage0.321
0.389Slugging percentage0.389
0.724OPS0.711
1.02Home runs per game1.15
8.80Hits per game8.06
50Home runs55
44Stolen bases32

Pitching

3.89ERA4.21
1.23WHIP1.39
8.75Strikeouts per nine7.24
3.51Walks per nine3.73
3.94Runs allowed per game4.23
0.225Opponent batting average0.256
434Pitching strikeouts349
18Quality starts18
8Saves17

Highlighted values lead the matchup; for points allowed, turnovers and similar stats, lower is better.

Odds

Sportsbook	Spread (STL)	Total	PIT ML	STL ML
DDraftKings	+1.5	7	-120	-101
FFanDuel	+1.5	7	-122	+104
BBetMGM	+1.5	7	-120	+100
CCaesars	+1.5	7	-125	+105
BBetOnline	+1.5	7	-115	+104
BBetRivers	+1.5	7	-132	+106
BBetus	+1.5	7	-115	+105
BBovada	+1.5	7	-118	-102
FFanatics	+1.5	7	-120	+100
LLowVig	+1.5	7	-115	+104
MMyBookie	+1.5	7	-116	-101

Game Information

Busch Stadium

Stadium

May 21, 2026

1:15 PM EDT

Gametime weather

Conditions pending

Lineups

PIT

Starters

STL

Starters

Rankings

Team	Offense	Defense
PIT	6th	16th
STL	11th	18th

Matchup

PITSTL

25-24Record28-20
51.0%Win %58.3%
13-13Home record13-12
12-11Road record15-8
4-6Last 105-5
1Streak-1
+22Run diff-1
10-8Division6-2
1 (B2B)Rest days1 (B2B)

Scores

Team	1	2	3	4	5	6	7	8	9	T
PIT	1	0	0	1	0	2	2	0	0	6
STL	0	0	1	0	0	0	0	1	0	2

Team Stats

PITStatSTL

6Runs2
10Hits8
0Errors0
2Home runs1
6RBI2
1Stolen bases0
9K (bat)11
11K (pit)9
2BB (pit)2

Player Stats

PIT — Batting

Player	AB	R	H	HR	RBI	BB
Oneil CruzCF	5	1	1	0	0	0
Bryan ReynoldsLF	5	0	0	0	1	0
Jake MangumLF	4	0	1	0	1	0
Brandon Lowe2B	4	1	2	1	1	1
Jared Triolo3B	4	0	1	0	0	0
Marcell OzunaDH	4	0	2	0	2	0
Konnor GriffinSS	4	2	1	0	0	0
Henry DavisC	3	1	1	1	1	0
Spencer Horwitz1B	3	1	1	0	0	1

PIT — Pitching

Player	IP	H	R	ER	BB	K
Braxton AshcraftSP	7.0	4	1	1	2	9
Wilber DotelRP	1.0	3	1	1	0	2
Mason MontgomeryRP	1.0	1	0	0	0	0

STL — Batting

Player	AB	R	H	HR	RBI	BB
Jose FerminLF	4	0	1	0	0	0
Pedro PagesC	4	0	2	0	0	0
Ivan HerreraDH	4	2	2	1	1	0
Nolan Gorman3B	4	0	0	0	0	0
Alec Burleson1B	4	0	2	0	0	0
JJ Wetherholt2B	4	0	0	0	0	0
Jordan WalkerRF	4	0	1	0	1	0
Victor Scott IICF	3	0	0	0	0	0
Masyn WinnSS	2	0	0	0	0	2
Yohel PozoC	1	0	0	0	0	0

STL — Pitching

Player	IP	H	R	ER	BB	K
Dustin MaySP	5.1	6	4	4	2	7
Matt SvansonRP	1.1	1	0	0	0	1
Matt PushardRP	1.0	0	0	0	0	1
Justin BruihlRP	0.2	3	2	2	0	0
Gordon GraceffoRP	0.2	0	0	0	0	0

Scoring Summary

83 events · 7 scoring

Inning 1 Top

Top
Cruz struck out looking.
0-0
Top
Lowe homered to left (342 feet).
1-0
Top
Reynolds struck out swinging.
1-0
Top
Horwitz fouled out to third.
1-0

Inning 1 Bottom

Bottom
Wetherholt struck out swinging.
1-0
Bottom
Herrera struck out looking.
1-0
Bottom
Burleson struck out looking.
1-0

Inning 2 Top

Top
Griffin grounded out to first.
1-0
Top
Ozuna grounded out to second.
1-0
Top
Mangum struck out swinging.
1-0

Inning 2 Bottom

Bottom
Walker grounded out to shortstop.
1-0
Bottom
Gorman fouled out to third.
1-0
Bottom
Winn walked.
1-0
Bottom
Fermín singled to left, Winn to second.
1-0
Bottom
Pagés grounded out to first.
1-0

Inning 3 Top

Top
Triolo flied out to right.
1-0
Top
Davis hit by pitch.
1-0
Top
Cruz struck out swinging.
1-0
Top
Lowe walked, Davis to second.
1-0
Top
Reynolds grounded out to pitcher.
1-0

Inning 3 Bottom

Bottom
Scott II flied out to center.
1-0
Bottom
Wetherholt struck out looking.
1-0
Bottom
Herrera homered to left center (408 feet).
1-1
Bottom
Burleson doubled to left.
1-1
Bottom
Walker struck out swinging.
1-1

Inning 4 Top

Top
Horwitz singled to center.
1-1
Top
Griffin grounded into fielder's choice to shortstop, Horwitz out at second.
1-1
Top
Griffin stole second.
1-1
Top
Ozuna singled to right, Griffin to third.
1-1
Top
Mangum grounded into fielder's choice to second, Griffin scored, Ozuna out at second.
2-1
Top
Triolo struck out swinging.
2-1

Inning 4 Bottom

Bottom
Gorman struck out swinging.
2-1
Bottom
Braxton Ashcraft challenged (pitch result), call on the field was confirmed: Masyn Winn walks.
2-1
Bottom
Fermín grounded out to pitcher, Winn to second.
2-1
Bottom
Pagés grounded out to shortstop.
2-1

Inning 5 Top

Top
Davis popped out to first.
2-1
Top
Cruz struck out swinging.
2-1
Top
Lowe grounded out to second.
2-1

Inning 5 Bottom

Bottom
Scott II flied out to left.
2-1
Bottom
Wetherholt popped out to third.
2-1
Bottom
Iván Herrera challenged (pitch result), call on the field was confirmed: Iván Herrera called out on strikes.
2-1

Inning 6 Top

Top
Pedro Pagés challenged (pitch result), call on the field was overturned: Bryan Reynolds called out on strikes.
2-1
Top
Horwitz walked.
2-1
Top
Griffin doubled to right, Horwitz to third.
2-1
Top
Ozuna singled to left, Horwitz scored and Griffin scored.
4-1
Top
Mangum singled to left, Ozuna to second.
4-1
Top
Graceffo relieved May
4-1
Top
Triolo grounded into double play, third to first, Ozuna out at third.
4-1

Inning 6 Bottom

Bottom
Burleson struck out swinging.
4-1
Bottom
Walker fouled out to first.
4-1
Bottom
Gorman struck out looking.
4-1

Inning 7 Top

Top
Bruihl relieved Graceffo
4-1
Top
Davis homered to left (375 feet).
5-1
Top
Cruz doubled to right.
5-1
Top
Lowe singled to left, Cruz to third.
5-1
Top
Reynolds grounded out to shortstop, Cruz scored, Lowe to second.
6-1
Top
Horwitz flied out to left.
6-1
Top
Svanson relieved Bruihl
6-1
Top
Griffin grounded out to third.
6-1

Inning 7 Bottom

Bottom
Winn grounded out to second.
6-1
Bottom
Fermín popped out to shortstop.
6-1
Bottom
Pagés singled to center.
6-1
Bottom
Scott II lined out to right.
6-1

Inning 8 Top

Top
Ozuna grounded out to shortstop.
6-1
Top
Mangum grounded out to third.
6-1
Top
Triolo singled to center.
6-1
Top
Davis struck out swinging.
6-1

Inning 8 Bottom

Bottom
Dotel relieved Ashcraft
6-1
Bottom
Wetherholt flied out to left.
6-1
Bottom
Herrera singled to left.
6-1
Bottom
Burleson singled to right, Herrera to third.
6-1
Bottom
Walker singled to left, Herrera scored, Burleson to second.
6-2
Bottom
Gorman struck out swinging.
6-2
Bottom
Winn struck out looking.
6-2

Inning 9 Top

Top
Pushard relieved Svanson
6-2
Top
Cruz flied out to center.
6-2
Top
Lowe grounded out to second.
6-2
Top
Reynolds struck out looking.
6-2

Inning 9 Bottom

Bottom
Montgomery relieved Dotel
6-2
Bottom
Fermín grounded out to first.
6-2
Bottom
Pagés singled to center.
6-2
Bottom
Pozo hit for Scott II
6-2
Bottom
Pozo grounded into double play, third to second to first, Pagés out at second.
6-2

Pittsburgh Pirates vs St. Louis Cardinals AI sports predictions & season series →

Player props

Pittsburgh Pirates vs St. Louis Cardinals Player Props

Prop lines and results for the players in this game, by market.

Konnor Griffin
Home Runs: 1/19 over · last line 0.5
Konnor Griffin Home Runs props Konnor Griffin Hits Runs Rbis props Konnor Griffin Hits props
Marcell Ozuna
Home Runs: 2/19 over · last line 0.5
Marcell Ozuna Home Runs props Marcell Ozuna Walks props Marcell Ozuna Hits props
Matthew Liberatore
Strikeouts: 9/18 over · last line 5.5
Matthew Liberatore Strikeouts props Matthew Liberatore Hits Allowed props Matthew Liberatore Outs props
Oneil Cruz
Home Runs: 1/18 over · last line 0.5
Oneil Cruz Home Runs props Oneil Cruz Hits props Oneil Cruz RBIs props
Andre Pallante
Outs: 9/17 over · last line 11.5
Andre Pallante Outs props Andre Pallante Hits Allowed props Andre Pallante Strikeouts props
Michael McGreevy
Hits Allowed: 9/17 over · last line 4.5
Michael McGreevy Hits Allowed props Michael McGreevy Strikeouts props Michael McGreevy ER props
Esmerlyn Valdez
Home Runs: 2/16 over · last line 0.5
Esmerlyn Valdez Home Runs props Esmerlyn Valdez Walks props Esmerlyn Valdez Hits props
Henry Davis
Home Runs: 0/16 over · last line 0.5
Henry Davis Home Runs props Henry Davis Walks props Henry Davis Runs props
Mitch Keller
Outs: 6/15 over · last line 15.5
Mitch Keller Outs props Mitch Keller Strikeouts props Mitch Keller Hits Allowed props
Endy Rodriguez
Hits: 10/14 over · last line 0.5
Endy Rodriguez Hits props Endy Rodriguez Home Runs props Endy Rodriguez Walks props
Kyle Leahy
Hits Allowed: 8/14 over · last line 2.5
Kyle Leahy Hits Allowed props Kyle Leahy Outs props Kyle Leahy Strikeouts props
Bubba Chandler
Hits Allowed: 4/13 over · last line 4.5
Bubba Chandler Hits Allowed props Bubba Chandler Outs props Bubba Chandler Strikeouts props

League-wide markets: MLB Home Runs props · MLB Hits Runs Rbis props · MLB Hits props · MLB Walks props · MLB Strikeouts props · MLB Hits Allowed props · MLB Outs props · MLB RBIs props · MLB ER props · MLB Runs props

Pittsburgh Pirates vs St. Louis Cardinals: Final Score & Recap

The Pittsburgh Pirates beat the St. Louis Cardinals 6-2 in this MLB game at Busch Stadium on Thursday, May 21, 2026. The line score, team and player box scores, and scoring summary are in the Game Stats tab.

Team pages: Pittsburgh Pirates · St. Louis Cardinals

Pittsburgh Pirates vs St. Louis Cardinals Odds

DraftKings lists the St. Louis Cardinals at STL +1.5 on the run line, with the total set at 7. Moneylines are Pittsburgh Pirates -120 and St. Louis Cardinals -101. Those are the closing numbers; the odds table above compares every book we track.

See the full MLB odds board and the MLB schedule. Looking for a side rather than a line? See today's MLB picks. For the model's reasoning, read our AI MLB predictions.

Pittsburgh Pirates vs St. Louis Cardinals — Common Questions

Who won Pittsburgh Pirates vs St. Louis Cardinals?+

The Pittsburgh Pirates beat the St. Louis Cardinals 6-2 on May 21, 2026 at Busch Stadium. The full box score and line score are on this page.

What are the odds for Pittsburgh Pirates vs St. Louis Cardinals?+

Where was Pittsburgh Pirates vs St. Louis Cardinals played?+

The game was at Busch Stadium.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.