Houston Astros vs Chicago Cubs AI Sports Picks & Predictions

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MLB

Houston AstrosHOU

4–2

Final

Chicago CubsCHC

Wrigley Field

Team Season Averages

Houston AstrosLeads 8 of 18

Chicago CubsLeads 10 of 18

Batting

4.27Runs per game4.92
0.246Batting average0.242
0.321On-base percentage0.338
0.404Slugging percentage0.397
0.725OPS0.735
1.18Home runs per game1.16
8.27Hits per game8.20
60Home runs58
17Stolen bases33

Pitching

5.34ERA4.07
1.53WHIP1.23
8.70Strikeouts per nine8.15
5.02Walks per nine3.08
5.20Runs allowed per game4.02
0.255Opponent batting average0.236
431Pitching strikeouts402
12Quality starts16
11Saves10

Highlighted values lead the matchup; for points allowed, turnovers and similar stats, lower is better.

Odds

Sportsbook	Spread (CHC)	Total	HOU ML	CHC ML
DDraftKings	-1.5	7	+123	-148
FFanDuel	-1.5	7	+120	-142
BBetMGM	-1.5	7	+125	-150
CCaesars	-1.5	7	+130	-155
BBetOnline	-1.5	7	+127	-140
BBetRivers	-1.5	7	+123	-155
BBetus	-1.5	7	+126	-140
BBovada	-1.5	7	+126	-150
FFanatics	-1.5	6.5	+120	-145
LLowVig	-1.5	7	+127	-140
MMyBookie	-1.5	7	+121	-143

Game Information

Wrigley Field

Stadium

May 22, 2026

2:20 PM EDT

Gametime weather

Conditions pending

Lineups

HOU

Starters

CHC

Starters

Rankings

Team	Offense	Defense
HOU	18th	28th
CHC	6th	14th

Matchup

HOUCHC

20-31Record29-21
39.2%Win %58.0%
12-14Home record18-8
8-17Road record11-13
4-6Last 102-8
-1Streak-5
-56Run diff+28
6-12Division5-5
2Rest days2

Scores

Team	1	2	3	4	5	6	7	8	9	T
HOU	0	0	1	2	1	0	0	0	0	4
CHC	0	0	0	0	0	2	0	0	0	2

Team Stats

HOUStatCHC

4Runs2
9Hits4
2Errors0
1Home runs1
4RBI2
0Stolen bases1
10K (bat)6
6K (pit)10
5BB (pit)4

Player Stats

HOU — Batting

Player	AB	R	H	HR	RBI	BB
Jeremy PenaSS	5	0	1	0	0	0
Christian Walker1B	5	1	1	0	0	0
Cam SmithRF	4	0	1	0	0	0
Zach ColeLF	4	0	0	0	1	0
Jake MeyersCF	4	0	1	0	0	0
Isaac Paredes3B	4	1	1	0	0	1
Christian VazquezC	4	1	2	1	2	0
Yordan AlvarezDH	3	0	1	0	0	2
Brice MatthewsCF	2	0	1	0	1	0
Braden ShewmakeSS	1	1	0	0	0	1
Nick AllenSS	0	0	0	0	0	0

HOU — Pitching

Player	IP	H	R	ER	BB	K
Spencer ArrighettiSP	5.0	2	0	0	4	5
Enyel De Los SantosRP	1.2	0	0	0	0	1
Bryan KingRP	1.1	0	0	0	0	0
Bryan AbreuRP	0.2	0	0	0	1	0
Steven OkertRP	0.1	2	2	2	0	0

CHC — Batting

Player	AB	R	H	HR	RBI	BB
Ian HappLF	5	0	1	0	0	0
Nico Hoerner2B	4	0	0	0	0	1
Seiya SuzukiRF	4	0	0	0	0	0
Dansby SwansonSS	4	0	0	0	0	0
Alex Bregman3B	3	0	1	0	0	1
Carson KellyC	3	0	0	0	0	0
Michael Busch1B	3	0	0	0	0	1
Michael ConfortoRF	2	0	0	0	0	0
Pete Crow-ArmstrongCF	2	1	1	1	2	2
Miguel AmayaC	1	1	1	0	0	0
Moises BallesterosDH	1	0	0	0	0	0

CHC — Pitching

Player	IP	H	R	ER	BB	K
Jameson TaillonSP	4.2	8	4	4	1	5
Ethan RobertsRP	2.0	0	0	0	1	2
Jacob WebbRP	1.0	0	0	0	0	2
Phil MatonRP	1.0	0	0	0	2	1
Hoby MilnerRP	0.1	1	0	0	0	0

Scoring Summary

97 events · 5 scoring

Inning 1 Top

Top
Peña singled to left.
0-0
Top
Paredes lined out to center.
0-0
Top
Alvarez struck out swinging.
0-0
Top
Walker struck out swinging.
0-0

Inning 1 Bottom

Bottom
Hoerner struck out swinging.
0-0
Bottom
Busch lined out to shortstop.
0-0
Bottom
Bregman singled to center.
0-0
Bottom
Happ doubled to left, Bregman to third.
0-0
Bottom
Suzuki grounded out to third.
0-0

Inning 2 Top

Top
Meyers singled to left.
0-0
Top
Shewmake flied out to left.
0-0
Top
Smith flied out to center.
0-0
Top
Cole struck out swinging.
0-0

Inning 2 Bottom

Bottom
Conforto struck out swinging.
0-0
Bottom
Kelly struck out swinging.
0-0
Bottom
Crow-Armstrong walked.
0-0
Bottom
Crow-Armstrong to third on pickoff error by pitcher Arrighetti.
0-0
Bottom
Swanson popped out to first.
0-0

Inning 3 Top

Top
Vázquez homered to left center (371 feet).
1-0
Top
Peña struck out swinging.
1-0
Top
Paredes grounded out to third.
1-0
Top
Alvarez flied out to left.
1-0

Inning 3 Bottom

Bottom
Nico Hoerner challenged (pitch result), call on the field was overturned: Nico Hoerner walks.
1-0
Bottom
Hoerner stole second.
1-0
Bottom
Busch hit by pitch.
1-0
Bottom
Bregman hit by pitch, Busch to second, Hoerner to third.
1-0
Bottom
Happ struck out swinging.
1-0
Bottom
Suzuki popped out to shortstop.
1-0
Bottom
Conforto grounded out to shortstop.
1-0

Inning 4 Top

Top
Walker singled to center.
1-0
Top
Meyers struck out swinging.
1-0
Top
Shewmake walked, Walker to second.
1-0
Top
Smith reached on infield single to shortstop, Shewmake to second, Walker to third.
1-0
Top
Cole grounded into fielder's choice to shortstop, Walker scored, Smith out at second, Shewmake to third.
2-0
Top
Vázquez singled to right, Shewmake scored, Cole to third.
3-0
Top
Peña grounded out to second.
3-0

Inning 4 Bottom

Bottom
Kelly flied out to center.
3-0
Bottom
Crow-Armstrong popped out to third.
3-0
Bottom
Swanson flied out to right.
3-0

Inning 5 Top

Top
Paredes singled to right.
3-0
Top
Alvarez singled to right, Paredes to second.
3-0
Top
Walker flied out to left.
3-0
Top
Meyers grounded into fielder's choice to third, Alvarez out at second, Paredes to third.
3-0
Top
Milner relieved Taillon
3-0
Top
Matthews hit for Shewmake
3-0
Top
Matthews singled to center, Paredes scored, Meyers to second.
4-0
Top
Smith grounded out to pitcher.
4-0

Inning 5 Bottom

Bottom
Matthews at second base.
4-0
Bottom
Hoerner flied out to center.
4-0
Bottom
Busch walked.
4-0
Bottom
Bregman walked, Busch to second.
4-0
Bottom
Happ struck out swinging.
4-0
Bottom
Suzuki lined out to right.
4-0

Inning 6 Top

Top
Roberts relieved Milner
4-0
Top
Cole grounded out to second.
4-0
Top
Vázquez struck out swinging.
4-0
Top
Peña grounded out to first.
4-0

Inning 6 Bottom

Bottom
Okert relieved Arrighetti
4-0
Bottom
Amaya hit for Conforto
4-0
Bottom
Amaya singled to center.
4-0
Bottom
Kelly flied out to right.
4-0
Bottom
Crow-Armstrong homered to right (406 feet), Amaya scored.
4-2
Bottom
De Los Santos relieved Okert
4-2
Bottom
Swanson struck out swinging.
4-2
Bottom
Hoerner flied out to second.
4-2

Inning 7 Top

Top
Amaya as designated hitter.
4-2
Top
Paredes grounded out to shortstop.
4-2
Top
Alvarez walked.
4-2
Top
Walker struck out swinging.
4-2
Top
Meyers grounded out to third.
4-2

Inning 7 Bottom

Bottom
Busch lined out to center.
4-2
Bottom
Bregman grounded out to third.
4-2
Bottom
Happ popped out to third.
4-2

Inning 8 Top

Top
Webb relieved Roberts
4-2
Top
Matthews struck out looking.
4-2
Top
Smith struck out swinging.
4-2
Top
Cole grounded out to first.
4-2

Inning 8 Bottom

Bottom
Allen at second base.
4-2
Bottom
Abreu relieved De Los Santos
4-2
Bottom
Suzuki grounded out to third.
4-2
Bottom
Ballesteros hit for Amaya
4-2
Bottom
Ballesteros flied out to center.
4-2
Bottom
Kelly hit by pitch.
4-2
Bottom
Crow-Armstrong walked, Kelly to second.
4-2
Bottom
King relieved Abreu
4-2
Bottom
Swanson safe at first on throwing error by shortstop Peña, Crow-Armstrong to second, Kelly to third.
4-2
Bottom
Hoerner grounded into fielder's choice to third, Swanson out at second.
4-2

Inning 9 Top

Top
Ballesteros as designated hitter.
4-2
Top
Maton relieved Webb
4-2
Top
Vázquez grounded out to shortstop.
4-2
Top
Peña lined out to right.
4-2
Top
Paredes walked.
4-2
Top
Alvarez walked, Paredes to second.
4-2
Top
Walker struck out swinging.
4-2

Inning 9 Bottom

Bottom
Busch flied out to left.
4-2
Bottom
Bregman flied out to center.
4-2
Bottom
Happ popped out to first.
4-2

Houston Astros vs Chicago Cubs AI sports predictions & season series →

Player props

Houston Astros vs Chicago Cubs Player Props

Prop lines and results for the players in this game, by market.

Carlos Correa
RBIs: 6/22 over · last line 0.5
Carlos Correa RBIs props Carlos Correa Walks props Carlos Correa Hits props
Daulton Varsho
Home Runs: 3/22 over · last line 0.5
Daulton Varsho Home Runs props Daulton Varsho Hits props Daulton Varsho Hits Runs Rbis props
Shota Imanaga
Outs: 6/20 over · last line 11.5
Shota Imanaga Outs props Shota Imanaga Strikeouts props Shota Imanaga Hits Allowed props
Yainer Diaz
Hits: 12/20 over · last line 0.5
Yainer Diaz Hits props Yainer Diaz Hits Runs Rbis props Yainer Diaz Home Runs props
Christian Vazquez
Hits: 8/17 over · last line 0.5
Christian Vazquez Hits props Christian Vazquez Hits Runs Rbis props Christian Vazquez Home Runs props
Hunter Brown
Outs: 6/15 over · last line 15.5
Hunter Brown Outs props Hunter Brown Strikeouts props Hunter Brown Hits Allowed props
Pedro Ramirez
Home Runs: 0/15 over · last line 0.5
Pedro Ramirez Home Runs props Pedro Ramirez Hits props Pedro Ramirez Hits Runs Rbis props
Kevin Gausman
Strikeouts: 10/14 over · last line 4.5
Kevin Gausman Strikeouts props Kevin Gausman Hits Allowed props Kevin Gausman Outs props
Miguel Amaya
Home Runs: 0/14 over · last line 0.5
Miguel Amaya Home Runs props Miguel Amaya Walks props Miguel Amaya Hits props
Peter Lambert
Hits Allowed: 7/14 over · last line 5.5
Peter Lambert Hits Allowed props Peter Lambert Strikeouts props Peter Lambert Outs props
Matthew Boyd
Strikeouts: 6/13 over · last line 3.5
Matthew Boyd Strikeouts props Matthew Boyd Hits Allowed props Matthew Boyd ER props
Clay Holmes
ER: 5/12 over · last line 1.5
Clay Holmes ER props Clay Holmes Hits Allowed props Clay Holmes Outs props

League-wide markets: MLB RBIs props · MLB Walks props · MLB Hits props · MLB Home Runs props · MLB Hits Runs Rbis props · MLB Outs props · MLB Strikeouts props · MLB Hits Allowed props · MLB ER props

Houston Astros vs Chicago Cubs: Final Score & Recap

The Houston Astros beat the Chicago Cubs 4-2 in this MLB game at Wrigley Field on Friday, May 22, 2026. The line score, team and player box scores, and scoring summary are in the Game Stats tab.

Team pages: Houston Astros · Chicago Cubs

Houston Astros vs Chicago Cubs Odds

DraftKings lists the Chicago Cubs at CHC -1.5 on the run line, with the total set at 7. Moneylines are Houston Astros +123 and Chicago Cubs -148. Those are the closing numbers; the odds table above compares every book we track.

See the full MLB odds board and the MLB schedule. Looking for a side rather than a line? See today's MLB picks. For the model's reasoning, read our AI MLB predictions.

Houston Astros vs Chicago Cubs — Common Questions

Who won Houston Astros vs Chicago Cubs?+

The Houston Astros beat the Chicago Cubs 4-2 on May 22, 2026 at Wrigley Field. The full box score and line score are on this page.

What are the odds for Houston Astros vs Chicago Cubs?+

Where was Houston Astros vs Chicago Cubs played?+

The game was at Wrigley Field.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.