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St. Louis Cardinals vs Pittsburgh Pirates

St. Louis CardinalsSTL
Tue, Sep 2210:40 PM UTC
Pittsburgh PiratesPIT

PNC Park

Team Season Average

STLPIT

Batting

4.51
R/G
4.79
0.242
AVG
0.254
0.315
OBP
0.332
0.382
SLG
0.406
0.697
OPS
0.737
1.03
HR/G
1.16
8.19
H/G
8.74
161
HR
181
97
SB
128

Pitching

4.29
ERA
4.19
1.36
WHIP
1.30
7.98
K/9
9.24
3.51
BB/9
3.64
4.26
RA/G
4.15
0.254
OPP AVG
0.238
1235
K
1429
53
QS
45
46
SV
38

Odds

SportsbookSpread (PIT)TotalSTL MLPIT ML
DDraftKings-1.57+143-174
FFanDuel-1.57.5+144-172
BBetMGM-1.57.5+145-175
CCaesars-1.57.5+141-164
BBetOnline-1.57+149-165
BBetRivers-1.57+145-177
BBetus-1.57+146-165
BBovada-1.57+144-175
FFanatics-1.57+145-175
LLowVig-1.57+149-165
MMyBookie-1.57+144-170

St. Louis Cardinals vs Pittsburgh Pirates: Matchup Preview

The St. Louis Cardinals visit the Pittsburgh Pirates in this MLB game, which throws its first pitch on Tuesday, September 22, 2026 at 6:40 PM ET at PNC Park. The St. Louis Cardinals come in with 2 days of rest; the Pittsburgh Pirates have 2 days of rest.

Team pages: St. Louis Cardinals · Pittsburgh Pirates

St. Louis Cardinals vs Pittsburgh Pirates Odds

DraftKings lists the Pittsburgh Pirates at PIT -1.5 on the run line, with the total set at 7. Moneylines are St. Louis Cardinals +143 and Pittsburgh Pirates -174. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

See the full MLB odds board and the MLB schedule. Looking for a side rather than a line? See today's MLB picks. For the model's reasoning, read our AI MLB predictions.

St. Louis Cardinals vs Pittsburgh Pirates— Common Questions

When do the St. Louis Cardinals play the Pittsburgh Pirates?+

St. Louis Cardinals at Pittsburgh Pirates throws its first pitch on Tuesday, September 22, 2026 at 6:40 PM ET at PNC Park. Times are shown in Eastern Time.

What are the odds for St. Louis Cardinals vs Pittsburgh Pirates?+

DraftKings lists the Pittsburgh Pirates at PIT -1.5 on the run line, with the total set at 7. Moneylines are St. Louis Cardinals +143 and Pittsburgh Pirates -174. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

Where is St. Louis Cardinals vs Pittsburgh Pirates being played?+

The game is at PNC Park.

Where can I follow the St. Louis Cardinals vs Pittsburgh Pirates live score?+

This page carries the live score, the period-by-period line score, and the box score while the game is on, then the final result and full stats once it ends.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.