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Kansas City Chiefs vs Buffalo Bills

Kansas City ChiefsKC
Thu, Nov 268:20 PM EST
Buffalo BillsBUF

Highmark Stadium · Buffalo

Team Season Averages

Kansas City ChiefsLeads 4 of 9
vs
Buffalo BillsLeads 5 of 9

Offense

  • 25.3Points per game32.0
  • 384.1Total yards per game386.4
  • 246.4Passing yards per game239.8
  • 137.8Rushing yards per game146.6

Defense

  • 17.9Points allowed per game23.4
  • 307.9Yards allowed per game330.4

Efficiency

  • 41.7%Third-down conversion rate43.2%
  • 63.3%Red-zone scoring rate66.7%
  • 0.9Turnovers per game1.5

Highlighted values lead the matchup; for points allowed, turnovers and similar stats, lower is better.

Odds

SportsbookSpread (BUF)TotalKC MLBUF ML
DDraftKings-2.550.5+124-148
FFanDuel-2.550.5+130-154
CCaesars-351.5+150-178

Kansas City Chiefs vs Buffalo Bills Projected Starting Lineups

Official starters post at kickoff. Projections repeat each team's last starting lineup, with this week's injury statuses marked.

Kansas City Chiefs

Projected starters, based on KC's Week 9 lineup

Buffalo Bills

Projected starters, based on BUF's Week 8 lineup

Player props

Kansas City Chiefs vs Buffalo Bills Player Props

Prop lines and results for the players in this game, by market.

League-wide markets: NFL Receiving Yards props · NFL Receptions props · NFL Rushing Yards props · NFL Passing Yards props · NFL Passing Touchdowns props · NFL Kicking Points props

Kansas City Chiefs vs Buffalo Bills: Matchup Preview

The Kansas City Chiefs (6-2) visit the Buffalo Bills (7-1) in this NFL game, which kicks off on Thursday, November 26, 2026 at 8:20 PM ET at Highmark Stadium, Buffalo.

Team pages: Kansas City Chiefs · Buffalo Bills

Kansas City Chiefs vs Buffalo Bills Odds

DraftKings lists the Buffalo Bills at BUF -2.5 on the spread, with the total set at 50.5. Moneylines are Kansas City Chiefs +124 and Buffalo Bills -148. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

See the full NFL odds board and the NFL schedule. Looking for a side rather than a line? See today's NFL picks. For the model's reasoning, read our AI NFL predictions.

Kansas City Chiefs vs Buffalo Bills — Common Questions

When do the Kansas City Chiefs play the Buffalo Bills?+

Kansas City Chiefs at Buffalo Bills kicks off on Thursday, November 26, 2026 at 8:20 PM ET at Highmark Stadium, Buffalo. Times are shown in Eastern Time.

What are the odds for Kansas City Chiefs vs Buffalo Bills?+

DraftKings lists the Buffalo Bills at BUF -2.5 on the spread, with the total set at 50.5. Moneylines are Kansas City Chiefs +124 and Buffalo Bills -148. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

Where is Kansas City Chiefs vs Buffalo Bills being played?+

The game is at Highmark Stadium, Buffalo.

Where can I follow the Kansas City Chiefs vs Buffalo Bills live score?+

This page carries the live score, the period-by-period line score, and the box score while the game is on, then the final result and full stats once it ends.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.

More NFL Week 12 predictions: NFL Week 12 best bets and the Week 12 schedule.

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