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Buffalo Bills vs Denver Broncos

Buffalo BillsBUF
Fri, Dec 254:30 PM EST
Denver BroncosDEN

Empower Field at Mile High · Denver

Team Season Averages

Buffalo BillsLeads 7 of 9
vs
Denver BroncosLeads 2 of 9

Offense

  • 32.0Points per game22.0
  • 386.4Total yards per game277.3
  • 239.8Passing yards per game185.9
  • 146.6Rushing yards per game91.4

Defense

  • 23.4Points allowed per game20.7
  • 330.4Yards allowed per game355.0

Efficiency

  • 43.2%Third-down conversion rate32.4%
  • 66.7%Red-zone scoring rate63.0%
  • 1.5Turnovers per game0.8

Highlighted values lead the matchup; for points allowed, turnovers and similar stats, lower is better.

Odds

SportsbookSpread (DEN)TotalBUF MLDEN ML
DDraftKings+1.546.5-130+110
FFanDuel+1.546.5-132+112
CCaesars+147.5-116-106

Buffalo Bills vs Denver Broncos Projected Starting Lineups

Official starters post at kickoff. Projections repeat each team's last starting lineup, with this week's injury statuses marked.

Buffalo Bills

Projected starters, based on BUF's Week 8 lineup

Denver Broncos

Projected starters, based on DEN's Week 9 lineup

Player props

Buffalo Bills vs Denver Broncos Player Props

Prop lines and results for the players in this game, by market.

League-wide markets: NFL Passing Yards props · NFL Passing Touchdowns props · NFL Rushing Yards props · NFL Receiving Yards props · NFL Receptions props · NFL Kicking Points props

Buffalo Bills vs Denver Broncos: Matchup Preview

The Buffalo Bills (7-1) visit the Denver Broncos (7-2) in this NFL game, which kicks off on Friday, December 25, 2026 at 4:30 PM ET at Empower Field at Mile High, Denver.

Team pages: Buffalo Bills · Denver Broncos

Buffalo Bills vs Denver Broncos Odds

DraftKings lists the Denver Broncos at DEN +1.5 on the spread, with the total set at 46.5. Moneylines are Buffalo Bills -130 and Denver Broncos +110. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

See the full NFL odds board and the NFL schedule. Looking for a side rather than a line? See today's NFL picks. For the model's reasoning, read our AI NFL predictions.

Buffalo Bills vs Denver Broncos — Common Questions

When do the Buffalo Bills play the Denver Broncos?+

Buffalo Bills at Denver Broncos kicks off on Friday, December 25, 2026 at 4:30 PM ET at Empower Field at Mile High, Denver. Times are shown in Eastern Time.

What are the odds for Buffalo Bills vs Denver Broncos?+

DraftKings lists the Denver Broncos at DEN +1.5 on the spread, with the total set at 46.5. Moneylines are Buffalo Bills -130 and Denver Broncos +110. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

Where is Buffalo Bills vs Denver Broncos being played?+

The game is at Empower Field at Mile High, Denver.

Where can I follow the Buffalo Bills vs Denver Broncos live score?+

This page carries the live score, the period-by-period line score, and the box score while the game is on, then the final result and full stats once it ends.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.

More NFL Week 16 predictions: NFL Week 16 best bets and the Week 16 schedule.

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