Detroit Lions vs Buffalo Bills AI Sports Picks & Predictions

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NFL

Detroit LionsDET

31–41

Final

Buffalo BillsBUF

Highmark Stadium

Team Season Averages

Season averages are not available for this game yet.

Odds

Sportsbook	Spread (BUF)	Total	DET ML	BUF ML
DDraftKings	-19.5	57.5	+1240	-2300
FFanDuel	-18.5	57.5	+1100	-4000
BBetMGM	-18.5	57.5	+1100	-2500
CCaesars	-18.5	58.5	+900	-2500
BBetOnline	-5.5	54.5	+212	-257
BBetRivers	-18	57.5	+1200	-5000
BBetus	-5.5	54.5	+210	-250
BBovada	-19.5	58	+750	-1600
FFanatics	-18.5	57.5	+1000	-2200
LLowVig	-5.5	54.5	+212	-257

Detroit Lions vs Buffalo Bills Starting Lineups

Detroit Lions

Starters

Offense

Defense

Inactives

Injury Report

Buffalo Bills

Starters

Offense

Defense

Inactives

98
T.J. Sanders
QuestionableDT
26
Ty Johnson
QuestionableRB
91
Ed Oliver
DT
60
Ar'maj Reed-Adams
G
74
Jude Bowry
OT
11
Kyle Allen
QB
29
Jalon Kilgore
S
13
Skyler Bell
WR

Injury Report

9
Bradley Chubb
LB
8
Terrel Bernard
LB
24
Cole Bishop
Knee, Groin
QuestionableS
37
Jordan Hancock
CB
98
T.J. Sanders
Knee, Illness
QuestionableDT
26
Ty Johnson
Hamstring
QuestionableRB

Scores

Team	Q1	Q2	Q3	Q4	T
DET	0	10	7	14	31
BUF	14	13	7	7	41

Team Stats

DETStatBUF

355Total yards446
289Passing yards243
66Rushing yards203
24First downs34
4-113rd down9-12
3-4Red zone5-5
0Turnovers0
4Sacks2
10-58Penalties5-46
26:15Possession33:45

Player Stats

DET — Passing

Player	C/ATT	YDS	TD	INT	RTG
Jared GoffQB	26/38	327	4	0	130.0

DET — Rushing

Player	CAR	YDS
Jahmyr GibbsRB	16	52
Jared GoffQB	3	7
Sione VakiRB	1	7

DET — Receiving

Player	REC	TGT	YDS	TD
Amon-Ra St. BrownWR	9	13	142	2
Jahmyr GibbsRB	6	8	61	1
Sam LaPortaTE	6	7	52	1
Jameson WilliamsWR	2	4	33	0
Isaac TeSlaaWR	2	5	26	0
Sione VakiRB	1	1	13	0

DET — Kicking

Player	FG	XP
Jake BatesPK	1/1	4/4

BUF — Passing

Player	C/ATT	YDS	TD	INT	RTG
Josh AllenQB	20/31	248	3	0	121.4

BUF — Rushing

Player	CAR	YDS	TD
James Cook IIIRB	21	135	1
Josh AllenQB	14	69	2
DJ MooreWR	1	-1	0

BUF — Receiving

Player	REC	TGT	YDS	TD
Dalton KincaidTE	7	8	95	1
Keon ColemanWR	6	6	63	0
Joshua PalmerWR	1	3	43	1
Khalil ShakirWR	3	6	38	0
Dawson KnoxTE	2	2	5	1
James Cook IIIRB	1	3	4	0

BUF — Kicking

Player	FG	XP
Tyler BassPK	0/0	5/5

Scoring Summary

14 events

1st Quarter

13:48BUF
J.Allen sacked at BUF 32 for -4 yards (A.Hutchinson). FUMBLES (A.Hutchinson) [A.Hutchinson], recovered by BUF-S.Brown at BUF 31.
0-0
9:09BUF
(No Huddle) J.Allen left guard for 1 yard, TOUCHDOWN. T.Bass extra point is GOOD, Center-R.Ferguson, Holder-T.Doman.
0-7
3:42BUF
(Shotgun) J.Allen pass deep middle to J.Palmer for 43 yards, TOUCHDOWN [S.Gill-Howard]. T.Bass extra point is GOOD, Center-R.Ferguson, Holder-T.Doman.
0-14
2:25DET
J.Goff sacked at 50 for -9 yards (G.Rousseau). FUMBLES (G.Rousseau) [G.Rousseau], recovered by DET-B.Wright at DET 49.
0-14
1:44DET
(Shotgun) J.Goff FUMBLES (Aborted) at DET 44, and recovers at DET 38.
0-14

2nd Quarter

11:48BUF
J.Allen pass short right to D.Knox for 1 yard, TOUCHDOWN. T.Bass extra point is GOOD, Center-R.Ferguson, Holder-T.Doman.
0-21
5:03DET
(Shotgun) J.Goff pass short right to J.Gibbs for 11 yards, TOUCHDOWN. J.Bates extra point is GOOD, Center-H.Hatten, Holder-J.Fox.
7-21
2:52BUF
(Shotgun) J.Allen pass deep middle to D.Kincaid for 16 yards, TOUCHDOWN. T.Bass extra point is No Good, Wide Left, Center-R.Ferguson, Holder-T.Doman.
7-27
0:00DET
J.Bates 31 yard field goal is GOOD, Center-H.Hatten, Holder-J.Fox.
10-27

3rd Quarter

9:29DET
(Shotgun) J.Goff pass short left to A.St. Brown for 2 yards, TOUCHDOWN. J.Bates extra point is GOOD, Center-H.Hatten, Holder-J.Fox.
17-27
1:07BUF
J.Allen scrambles right end for 2 yards, TOUCHDOWN. T.Bass extra point is GOOD, Center-R.Ferguson, Holder-T.Doman.
17-34

4th Quarter

10:53DET
J.Goff pass short left to S.LaPorta for 1 yard, TOUCHDOWN. J.Bates extra point is GOOD, Center-H.Hatten, Holder-J.Fox.
24-34
2:50BUF
J.Cook right tackle for 1 yard, TOUCHDOWN. T.Bass extra point is GOOD, Center-R.Ferguson, Holder-T.Doman.
24-41
1:42DET
(Shotgun) J.Goff pass deep middle to A.St. Brown for 27 yards, TOUCHDOWN [M.Danna]. J.Bates extra point is GOOD, Center-H.Hatten, Holder-J.Fox.
31-41

Player props

Detroit Lions vs Buffalo Bills Player Props

Prop lines and results for the players in this game, by market.

Amon-Ra St. Brown
Receiving Yards: 3/8 over · last line 79.5
Amon-Ra St. Brown Receiving Yards props & line Amon-Ra St. Brown Receptions props
Jahmyr Gibbs
Rushing Yards: 5/8 over · last line 98.5
Jahmyr Gibbs Rushing Yards props & line Jahmyr Gibbs Receiving Yards props Jahmyr Gibbs Receptions props
Jameson Williams
Receiving Yards: 3/8 over · last line 51.5
Jameson Williams Receiving Yards props & line Jameson Williams Receptions props
Jared Goff
Passing Yards: 4/8 over · last line 258.5
Jared Goff Passing Yards props & line Jared Goff Passing Touchdowns props Jared Goff Rushing Yards props
Sam LaPorta
Receiving Yards: 4/8 over · last line 48.5
Sam LaPorta Receiving Yards props & line Sam LaPorta Receptions props
Dalton Kincaid
Receiving Yards: 3/7 over · last line 44.5
Dalton Kincaid Receiving Yards props & line Dalton Kincaid Receptions props
Dawson Knox
Receiving Yards: 1/7 over · last line 7.5
Dawson Knox Receiving Yards props & line Dawson Knox Receptions props
Isaac TeSlaa
Receiving Yards: 3/7 over · last line 16.5
Isaac TeSlaa Receiving Yards props & line Isaac TeSlaa Receptions props
Josh Allen
Passing Yards: 4/7 over · last line 249.5
Josh Allen Passing Yards props & line Josh Allen Passing Touchdowns props Josh Allen Rushing Yards props
Keon Coleman
Receiving Yards: 4/7 over · last line 30.5
Keon Coleman Receiving Yards props & line Keon Coleman Receptions props
Khalil Shakir
Receiving Yards: 4/7 over · last line 41.5
Khalil Shakir Receiving Yards props & line Khalil Shakir Receptions props
Sione Vaki
Rushing Yards: 4/7 over · last line 17.5
Sione Vaki Rushing Yards props & line
DJ Moore
Receiving Yards: 3/5 over · last line 54.5
DJ Moore Receiving Yards props & line DJ Moore Receptions props
Joshua Palmer
Receiving Yards: 3/4 over · last line 9.5
Joshua Palmer Receiving Yards props & line Joshua Palmer Receptions props
Ray Davis
Rushing Yards: 1/4 over · last line 4.5
Ray Davis Rushing Yards props & line
Ty Johnson
Rushing Yards: 1/3 over · last line 2.5
Ty Johnson Rushing Yards props & line Ty Johnson Receiving Yards props Ty Johnson Receptions props
Jake Bates
Kicking Points: 4/8 over · last line 8.5
Jake Bates Kicking Points props
Tyler Bass
Kicking Points: 4/7 over · last line 7.5
Tyler Bass Kicking Points props

League-wide markets: NFL Receiving Yards props · NFL Receptions props · NFL Rushing Yards props · NFL Passing Yards props · NFL Passing Touchdowns props · NFL Kicking Points props

Detroit Lions vs Buffalo Bills: Final Score & Recap

The Buffalo Bills beat the Detroit Lions 41-31 in this NFL game at Highmark Stadium on Thursday, September 17, 2026. The line score, team and player box scores, and scoring summary are in the Game Stats tab.

Team pages: Detroit Lions · Buffalo Bills

Detroit Lions vs Buffalo Bills Odds

DraftKings lists the Buffalo Bills at BUF -19.5 on the spread, with the total set at 57.5. Moneylines are Detroit Lions +1240 and Buffalo Bills -2300. Those are the closing numbers; the odds table above compares every book we track.

See the full NFL odds board and the NFL schedule. Looking for a side rather than a line? See today's NFL picks. For the model's reasoning, read our AI NFL predictions.

Detroit Lions vs Buffalo Bills — Common Questions

Who won Detroit Lions vs Buffalo Bills?+

The Buffalo Bills beat the Detroit Lions 41-31 on Sep 17, 2026 at Highmark Stadium. The full box score and line score are on this page.

What are the odds for Detroit Lions vs Buffalo Bills?+

Where was Detroit Lions vs Buffalo Bills played?+

The game was at Highmark Stadium.

Is Stat Sniper a sportsbook?+

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