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New England Patriots vs Buffalo Bills

New England PatriotsNE
Sun, Oct 45:00 PM UTC
Buffalo BillsBUF

Highmark Stadium · Unknown

Team Season Average

NEBUF

Offense

10.0
PPG
—
277.0
YDS/G
—
168.0
PASS/G
—
109.0
RUSH/G
—

Defense

13.0
OPP PPG
—
285.0
OPP YDS
—

Efficiency

31.3%
3RD %
—
50.0%
RZ %
—
3.0
TO/G
—

Odds

SportsbookSpread (BUF)TotalNE MLBUF ML
DDraftKings-5.549.5+205-250
FFanDuel-5.550.5+215-260
CCaesars-5.549.5+210-260
BBetOnline-5.550——
BBetRivers-5.549.5+210-265
BBetus-5.550.5——
LLowVig-5.550——
MMyBookie-5.550+189-250

New England Patriots vs Buffalo Bills: Matchup Preview

The New England Patriots (0-1) visit the Buffalo Bills (0-0) in this NFL game, which kicks off on Sunday, October 4, 2026 at 1:00 PM ET at Highmark Stadium, Unknown.

Team pages: New England Patriots · Buffalo Bills

New England Patriots vs Buffalo Bills Odds

DraftKings lists the Buffalo Bills at BUF -5.5 on the spread, with the total set at 49.5. Moneylines are New England Patriots +205 and Buffalo Bills -250. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

See the full NFL odds board and the NFL schedule. Looking for a side rather than a line? See today's NFL picks. For the model's reasoning, read our AI NFL predictions.

New England Patriots vs Buffalo Bills— Common Questions

When do the New England Patriots play the Buffalo Bills?+

New England Patriots at Buffalo Bills kicks off on Sunday, October 4, 2026 at 1:00 PM ET at Highmark Stadium, Unknown. Times are shown in Eastern Time.

What are the odds for New England Patriots vs Buffalo Bills?+

DraftKings lists the Buffalo Bills at BUF -5.5 on the spread, with the total set at 49.5. Moneylines are New England Patriots +205 and Buffalo Bills -250. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

Where is New England Patriots vs Buffalo Bills being played?+

The game is at Highmark Stadium, Unknown.

Where can I follow the New England Patriots vs Buffalo Bills live score?+

This page carries the live score, the period-by-period line score, and the box score while the game is on, then the final result and full stats once it ends.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.