Houston Astros vs Cleveland Guardians AI Sports Picks & Predictions

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MLB

Houston AstrosHOU

2–0

Final

Cleveland GuardiansCLE

Progressive Field

Team Season Averages

Houston AstrosLeads 9 of 18

Cleveland GuardiansLeads 9 of 18

Batting

5.40Runs per game4.20
0.262Batting average0.231
0.352On-base percentage0.321
0.438Slugging percentage0.383
0.790OPS0.704
1.20Home runs per game1.04
8.92Hits per game7.48
30Home runs26
12Stolen bases19

Pitching

6.05ERA4.08
1.65WHIP1.28
9.74Strikeouts per nine9.73
5.68Walks per nine3.72
5.84Runs allowed per game4.00
0.265Opponent batting average0.231
235Pitching strikeouts238
3Quality starts8
5Saves7

Highlighted values lead the matchup; for points allowed, turnovers and similar stats, lower is better.

Odds

Sportsbook	Spread (CLE)	Total	HOU ML	CLE ML
DDraftKings	-1.5	8	+139	-168
FFanDuel	-1.5	8	+136	-162
BBetMGM	-1.5	8	+135	-160
CCaesars	-1.5	8	+140	-165
BBetOnline	-1.5	8	+146	-161
BBetRivers	-1.5	8	+130	-162
BBetus	-1.5	8	+138	-155
BBovada	-1.5	8.5	+139	-165
FFanatics	-1.5	8.5	+140	-170
LLowVig	-1.5	8	+146	-161
MMyBookie	-1.5	8	+139	-164

Game Information

Progressive Field

Stadium

Apr 22, 2026

1:10 PM EDT

Gametime weather

Conditions pending

Lineups

HOU

Starters

CLE

Starters

Rankings

Team	Offense	Defense
HOU	4th	29th
CLE	20th	13th

Matchup

HOUCLE

9-16Record14-11
36.0%Win %56.0%
7-6Home record8-4
2-10Road record6-7
3-7Last 105-5
-1Streak1
-15Run diff-4
3-8Division2-1
1 (B2B)Rest days1 (B2B)

Scores

Team	1	2	3	4	5	6	7	8	9	T
HOU	2	0	0	0	0	0	0	0	0	2
CLE	0	0	0	0	0	0	0	0	0	0

Team Stats

HOUStatCLE

2Runs0
6Hits5
1Errors0
1Home runs0
2RBI0
0Stolen bases0
6K (bat)10
10K (pit)6
4BB (pit)3

Player Stats

HOU — Batting

Player	AB	R	H	HR	RBI	BB
Cam Smith3B	4	0	0	0	0	0
Jose Altuve2B	4	0	0	0	0	0
Carlos CorreaSS	4	1	1	0	0	0
Isaac Paredes3B	4	0	1	0	0	0
Daniel JohnsonCF	4	0	0	0	0	0
Yordan AlvarezLF	4	1	3	1	2	0
Christian Walker1B	3	0	1	0	0	1
Christian VazquezC	3	0	0	0	0	1
Brice MatthewsSS	2	0	0	0	0	1

HOU — Pitching

Player	IP	H	BB	K
Peter LambertRP	6.0	3	3	8
Enyel De Los SantosRP	1.1	1	1	1
AJ BlubaughSP	1.0	0	0	1
Steven OkertRP	0.2	1	0	0

CLE — Batting

Player	AB	H	BB
Jose Ramirez3B	4	1	0
George ValeraRF	4	0	0
Brayan RocchioSS	4	0	0
Chase DeLauterRF	4	2	0
Bo NaylorC	3	0	1
Juan BritoSS	3	0	0
Steven KwanLF	3	1	1
Daniel SchneemannSS	3	1	1
Kyle Manzardo1B	2	0	1
Rhys Hoskins1B	1	0	0
Angel MartinezCF	1	0	0

CLE — Pitching

Player	IP	H	R	ER	BB	K
Tanner BibeeSP	6.0	5	2	2	2	3
Matt FestaRP	1.0	0	0	0	1	2
Hunter GaddisRP	1.0	0	0	0	0	0
Erik SabrowskiRP	1.0	1	0	0	0	1

Scoring Summary

81 events · 1 scoring

Inning 1 Top

Top
Correa doubled to left.
0-0
Top
Alvarez homered to right center (422 feet), Correa scored.
2-0
Top
Altuve grounded out to shortstop.
2-0
Top
Walker popped out to first.
2-0
Top
Paredes struck out swinging.
2-0

Inning 1 Bottom

Bottom
Kwan grounded out to first.
2-0
Bottom
DeLauter grounded out to shortstop.
2-0
Bottom
Ramírez singled to right.
2-0
Bottom
Manzardo walked, Ramírez to second.
2-0
Bottom
Valera flied out to right.
2-0

Inning 2 Top

Top
Smith struck out looking.
2-0
Top
Johnson popped out to shortstop.
2-0
Top
Vázquez grounded out to first.
2-0

Inning 2 Bottom

Bottom
Schneemann walked.
2-0
Bottom
Brito struck out swinging.
2-0
Bottom
Naylor struck out swinging, Schneemann caught stealing second, catcher to shortstop.
2-0

Inning 3 Top

Top
Matthews walked.
2-0
Top
Correa grounded into double play, shortstop to second to first, Matthews out at second.
2-0
Top
Alvarez singled to right.
2-0
Top
Altuve lined out to left.
2-0

Inning 3 Bottom

Bottom
Rocchio bunt grounded out to third.
2-0
Bottom
Kwan singled to right.
2-0
Bottom
DeLauter singled to left, Kwan to second.
2-0
Bottom
Ramírez struck out swinging.
2-0
Bottom
Manzardo struck out swinging.
2-0

Inning 4 Top

Top
Walker walked.
2-0
Top
Paredes popped out to third.
2-0
Top
Smith struck out swinging.
2-0
Top
Johnson flied out to right.
2-0

Inning 4 Bottom

Bottom
Valera safe at first on fielding error by second baseman Altuve.
2-0
Bottom
Schneemann struck out swinging, Valera to second on wild pitch by Lambert.
2-0
Bottom
Brito grounded out to first, Valera to third.
2-0
Bottom
Naylor lined out to right.
2-0

Inning 5 Top

Top
Vázquez flied out to left.
2-0
Top
Matthews grounded out to third.
2-0
Top
Correa grounded out to shortstop.
2-0

Inning 5 Bottom

Bottom
Rocchio grounded out to first.
2-0
Bottom
Kwan walked.
2-0
Bottom
DeLauter popped out to third.
2-0
Bottom
Ramírez struck out swinging.
2-0

Inning 6 Top

Top
Alvarez singled to right.
2-0
Top
Altuve popped out to second.
2-0
Top
Walker singled to right, Alvarez to second.
2-0
Top
Paredes flied out to left.
2-0
Top
Smith grounded out to first.
2-0

Inning 6 Bottom

Bottom
Manzardo struck out swinging.
2-0
Bottom
Valera grounded out to pitcher.
2-0
Bottom
Schneemann struck out swinging.
2-0

Inning 7 Top

Top
Festa relieved Bibee
2-0
Top
Johnson struck out looking.
2-0
Top
Vázquez walked.
2-0
Top
Matthews flied out to left.
2-0
Top
Correa struck out swinging.
2-0

Inning 7 Bottom

Bottom
Blubaugh relieved Lambert
2-0
Bottom
Brito struck out swinging.
2-0
Bottom
Naylor fouled out to left.
2-0
Bottom
Rocchio grounded out to first.
2-0

Inning 8 Top

Top
Gaddis relieved Festa
2-0
Top
Alvarez grounded out to first.
2-0
Top
Altuve grounded out to third.
2-0
Top
Walker flied out to center.
2-0

Inning 8 Bottom

Bottom
Okert relieved Blubaugh
2-0
Bottom
Kwan grounded out to third.
2-0
Bottom
DeLauter singled to right.
2-0
Bottom
Ramírez grounded into fielder's choice to shortstop, DeLauter out at second.
2-0
Bottom
Hoskins hit for Manzardo
2-0
Bottom
De Los Santos relieved Okert
2-0
Bottom
Hoskins struck out swinging.
2-0

Inning 9 Top

Top
Hoskins at first base.
2-0
Top
Sabrowski relieved Gaddis
2-0
Top
Paredes singled to left.
2-0
Top
Smith lined out to right.
2-0
Top
Johnson lined out to center.
2-0
Top
Vázquez struck out swinging.
2-0

Inning 9 Bottom

Bottom
Valera lined out to left.
2-0
Bottom
Schneemann reached on infield single to second.
2-0
Bottom
Martínez hit for Brito
2-0
Bottom
Martínez flied out to right.
2-0
Bottom
Schneemann to second on fielder's indifference.
2-0
Bottom
Naylor walked.
2-0
Bottom
Rocchio flied out to center.
2-0

Houston Astros vs Cleveland Guardians AI sports predictions & season series →

Player props

Houston Astros vs Cleveland Guardians Player Props

Prop lines and results for the players in this game, by market.

Carlos Correa
RBIs: 6/22 over · last line 0.5
Carlos Correa RBIs props Carlos Correa Walks props Carlos Correa Hits props
Daulton Varsho
Home Runs: 3/22 over · last line 0.5
Daulton Varsho Home Runs props Daulton Varsho Hits props Daulton Varsho Hits Runs Rbis props
Yainer Diaz
Hits: 12/20 over · last line 0.5
Yainer Diaz Hits props Yainer Diaz Hits Runs Rbis props Yainer Diaz Home Runs props
Christian Vazquez
Hits: 8/17 over · last line 0.5
Christian Vazquez Hits props Christian Vazquez Hits Runs Rbis props Christian Vazquez Home Runs props
Nathaniel Lowe
Home Runs: 1/17 over · last line 0.5
Nathaniel Lowe Home Runs props Nathaniel Lowe RBIs props Nathaniel Lowe Walks props
Rhys Hoskins
Home Runs: 2/17 over · last line 0.5
Rhys Hoskins Home Runs props Rhys Hoskins Hits props Rhys Hoskins RBIs props
Gavin Williams
Strikeouts: 9/16 over · last line 6.5
Gavin Williams Strikeouts props Gavin Williams Hits Allowed props Gavin Williams Outs props
Parker Messick
Hits Allowed: 9/16 over · last line 4.5
Parker Messick Hits Allowed props Parker Messick Strikeouts props Parker Messick Walks props
Hunter Brown
Outs: 6/15 over · last line 15.5
Hunter Brown Outs props Hunter Brown Strikeouts props Hunter Brown Hits Allowed props
Austin Hedges
Home Runs: 2/14 over · last line 0.5
Austin Hedges Home Runs props Austin Hedges Hits Runs Rbis props Austin Hedges Walks props
Peter Lambert
Hits Allowed: 7/14 over · last line 5.5
Peter Lambert Hits Allowed props Peter Lambert Strikeouts props Peter Lambert Outs props
Foster Griffin
Strikeouts: 6/13 over · last line 3.5
Foster Griffin Strikeouts props Foster Griffin ER props Foster Griffin Hits Allowed props

League-wide markets: MLB RBIs props · MLB Walks props · MLB Hits props · MLB Home Runs props · MLB Hits Runs Rbis props · MLB Strikeouts props · MLB Hits Allowed props · MLB Outs props · MLB ER props

Houston Astros vs Cleveland Guardians: Final Score & Recap

The Houston Astros beat the Cleveland Guardians 2-0 in this MLB game at Progressive Field on Wednesday, April 22, 2026. The line score, team and player box scores, and scoring summary are in the Game Stats tab.

Team pages: Houston Astros · Cleveland Guardians

Houston Astros vs Cleveland Guardians Odds

DraftKings lists the Cleveland Guardians at CLE -1.5 on the run line, with the total set at 8. Moneylines are Houston Astros +139 and Cleveland Guardians -168. Those are the closing numbers; the odds table above compares every book we track.

See the full MLB odds board and the MLB schedule. Looking for a side rather than a line? See today's MLB picks. For the model's reasoning, read our AI MLB predictions.

Houston Astros vs Cleveland Guardians — Common Questions

Who won Houston Astros vs Cleveland Guardians?+

The Houston Astros beat the Cleveland Guardians 2-0 on Apr 22, 2026 at Progressive Field. The full box score and line score are on this page.

What are the odds for Houston Astros vs Cleveland Guardians?+

Where was Houston Astros vs Cleveland Guardians played?+

The game was at Progressive Field.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.