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Cleveland Guardians vs Boston Red Sox

Cleveland GuardiansCLE
Tue, Sep 2210:45 PM UTC
Boston Red SoxBOS

Fenway Park

Team Season Average

CLEBOS

Batting

4.16
R/G
4.35
0.238
AVG
0.246
0.315
OBP
0.320
0.377
SLG
0.401
0.692
OPS
0.721
0.97
HR/G
1.03
7.94
H/G
8.24
152
HR
161
142
SB
103

Pitching

3.78
ERA
3.59
1.26
WHIP
1.24
9.59
K/9
8.78
3.33
BB/9
2.94
3.73
RA/G
3.54
0.236
OPP AVG
0.241
1476
K
1352
57
QS
63
44
SV
44

Odds

SportsbookSpread (BOS)TotalCLE MLBOS ML
DDraftKings-1.56.5+108-130
FFanDuel-1.56.5+110-130
BBetMGM-1.56.5+105-125
CCaesars-1.56.5+108-127
BBetOnline-1.56.5+109-120
BBetRivers-1.56.5+108-129
BBetus-1.56.5+111-122
BBovada-1.56.5+107-128
FFanatics-1.56.5+105-125
LLowVig-1.56.5+109-120
MMyBookie-1.56.5+109-128

Cleveland Guardians vs Boston Red Sox: Matchup Preview

The Cleveland Guardians visit the Boston Red Sox in this MLB game, which throws its first pitch on Tuesday, September 22, 2026 at 6:45 PM ET at Fenway Park. The Cleveland Guardians come in with 2 days of rest; the Boston Red Sox have 2 days of rest.

Team pages: Cleveland Guardians · Boston Red Sox

Cleveland Guardians vs Boston Red Sox Odds

DraftKings lists the Boston Red Sox at BOS -1.5 on the run line, with the total set at 6.5. Moneylines are Cleveland Guardians +108 and Boston Red Sox -130. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

See the full MLB odds board and the MLB schedule. Looking for a side rather than a line? See today's MLB picks. For the model's reasoning, read our AI MLB predictions.

Cleveland Guardians vs Boston Red Sox— Common Questions

When do the Cleveland Guardians play the Boston Red Sox?+

Cleveland Guardians at Boston Red Sox throws its first pitch on Tuesday, September 22, 2026 at 6:45 PM ET at Fenway Park. Times are shown in Eastern Time.

What are the odds for Cleveland Guardians vs Boston Red Sox?+

DraftKings lists the Boston Red Sox at BOS -1.5 on the run line, with the total set at 6.5. Moneylines are Cleveland Guardians +108 and Boston Red Sox -130. Lines move up to game time; the odds table above compares every book we track so you can shop the number.

Where is Cleveland Guardians vs Boston Red Sox being played?+

The game is at Fenway Park.

Where can I follow the Cleveland Guardians vs Boston Red Sox live score?+

This page carries the live score, the period-by-period line score, and the box score while the game is on, then the final result and full stats once it ends.

Is Stat Sniper a sportsbook?+

No. Stat Sniper does not accept wagers or hold funds. The scores, odds, and stats on this page are reference data — any bet you place happens at the sportsbook of your choice.